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Retraction Note: Bone mesenchymal stem cell-derivedexosomal microRNA-29b-3p preventshypoxic-ischemic injury in rat brain byactivating the PTEN-mediated Aktsignaling pathway
Journal of Neuroinflammation volume 17, Article number: 352 (2020)
The Original Article was published on 03 February 2020
Retraction to: J Neuroinflammation 17, 46 (2020)
https://0-doi-org.brum.beds.ac.uk/10.1186/s12974-020-1725-8
The authors have retracted this article [1] because they have been unable to replicate the results of their study. After publication they expanded the sample size and repeated the measurements, and found that miR-29b-3p was not always down-regulated in the rat MCAO model and OGD cell model. In addition, when the processing time was doubled, miR-29b-3p showed an upward trend. The conclusions presented are therefore not reliable. All authors agree with this retraction.
Reference
Hou K, Li G, Zhao J, Xu B, Yang Z, Yu J, Kan X. Bone mesenchymal stem cell-derived exosomal microRNA-29b-3p prevents hypoxic-ischemic injury in rat brain by activating the PTEN-mediated Akt signaling pathway. J Neuroinflammation. 2020;17:46 https://0-doi-org.brum.beds.ac.uk/10.1186/s12974-020-1725-8.
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Hou, K., Li, G., Zhao, J. et al. Retraction Note: Bone mesenchymal stem cell-derivedexosomal microRNA-29b-3p preventshypoxic-ischemic injury in rat brain byactivating the PTEN-mediated Aktsignaling pathway. J Neuroinflammation 17, 352 (2020). https://0-doi-org.brum.beds.ac.uk/10.1186/s12974-020-02034-6
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DOI: https://0-doi-org.brum.beds.ac.uk/10.1186/s12974-020-02034-6