Fig. 9From: Early glycolytic reprogramming controls microglial inflammatory activationProposed anti-neuroinflammatory mechanisms of glycolytic inhibition. Glycolytic inhibition suppressed LPS-induced activation of NF-κB signaling pathways by modulating NAD+/SIRT1/p65 and AMPK/mTOR/IKK/p65 signaling pathways. Therefore, inhibition of glycolysis reduced the death of DA neurons by suppressing microglial inflammatory activationBack to article page