Fig. 7

Cordycepin enhances adenosine receptors expression and ameliorates inflammatory cytokines expression after TBI. a, b Quantitative RT-PCR analysis cytokines on 3 days (a) and 7 days (b) after TBI. n=5~9/group. c Chemical structure of adenosine and cordycepin (from sigma website), the red circles indicate the difference between them. d Quantitative RT-PCR analysis of A1 and A2a receptors. n=4~5/group. e Representative images of A2a receptor expression and their heat maps. Scale bar: 1 mm. f Quantification of A2a receptor intensity surrounding the lesion. n=5/group. ^#p < 0.05, ^##p < 0.01, and ^###p < 0.001, or *p < 0.05, **p < 0.01, and ***p < 0.001 as indicated