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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Microglia RAGE exacerbates the progression of neurodegeneration within the SOD1G93A murine model of amyotrophic lateral sclerosis in a sex-dependent manner

Fig. 3

SOD1G93A mice exhibit increased RAGE+ microglia at the age of 120 days. a Representative images of CD11B and RAGE staining in the ventral horn of SOD1G93A mouse lumbar spinal cord. Scale bar: 50 μm. b Quantification of overlap of CD11B+ RAGE+ area. N = 3 male WT mice, N = 4 male SOD1G93A mice, N = 4 female WT mice, and N = 4 female SOD1G93A mice. Mean ± SD. Two-way ANOVA with post-hoc Tukey’s test. *p = 0.0192, ****p < 0.0001

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