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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Intravenous administration of LPS activates the kynurenine pathway in healthy male human subjects: a prospective placebo-controlled cross-over trial

Fig. 4

Associations between A metabolite ratios and CRP or IL-6 over all timepoints. The size of the circles indicates the strength of the association (−log10p), the color indicates the direction of the association (red: positive, blue: negative). *p < 0.0083. KYNA: kynureninic acid, QUIN: quinolinic acid. B Correlation between the maximum increase in CRP (mg/dL) and the maximum increase in the kynurenine/tryptophan ratio independent of time. The black line indicates the conditional mean, and the grey area indicates the 95% confidence interval

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