Fig. 2
From: AXL kinase-mediated astrocytic phagocytosis modulates outcomes of traumatic brain injury
Astrocytes become phagocytes, mediated by AXL, after traumatic brain injury in vivo. (A) Representative images of Fluoro-Jade signals (green) and GFAP + (red) brain sections at 3 dpi with or without drug treatment and FJ + degenerating neuronal debris enwrapped by GFAP + astrocytes. (B) Quantification analysis of phagocytic GFAP+ astrocytes at 3 dpi following R428 or rmGas6 administration. **p < 0.01 by one-way ANOVA. (C) Images identified the degree of astrocytic phagocytosis (FJ+ neuronal debris enwrapped by GFAP+ astrocytes). (D) Quantification of four subtypes of phagocytic astrocytes. n = 4 per group. *p < 0.05 by two-way ANOVA