Fig. 1

MCC950 treatment inhibits NLRP3 inflammasome activation 24 h post-SAH. A Representative western blot and densitometric analysis for NLRP3 and caspase-1 (p10 subunit). B Representative western blot and densitometric analysis of caspase-1 (p20 subunit). C Representative western blot and densitometric analysis for IL-1β. Data presented as mean ± SEM, * p < 0.05 compared to sham + vehicle group, ** p < 0.01 compared to sham + vehicle group by Kruskal-Wallis test with Dunn’s multiple comparisons test