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Figure 1 | Journal of Neuroinflammation

Figure 1

From: Toll-like receptor signaling adapter proteins govern spread of neuropathic pain and recovery following nerve injury in male mice

Figure 1

Schematic of the TLR pathways. (A) This figure highlights the key TLRs and their relevant pathways in this paper. TLR2, TLR4, and TLR5 are found on the cell surface, while TLR3 is in the cell endosomes. MyD88 is a key adaptor protein for all TLRs except TLR3. TLR3 and TLR4 signal through TRIF, resulting predominantly in type I interferon production. (B) This table summarizes the strains of mice used in the presented studies and the nomenclature used throughout the paper.

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Journal of Neuroinflammation

ISSN: 1742-2094