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Figure 1 | Journal of Neuroinflammation

Figure 1

From: LPS and TNF alpha modulate AMPA/NMDA receptor subunit expression and induce PGE2 and glutamate release in preterm fetal ovine mixed glial cultures

Figure 1

Pre-OL survival in activated mixed glial cultures exposed to AMPA or NMDA receptor antagonists. Immunocytochemistry was used to assess pre-OL survival in mixed glial cultures exposed to TNF-α (A) or LPS (B) alone or without (C) or in combination with NBQX, MK-801, or combined NBQX/MK-801. Data are presented as mean pre-OL survival as a percentage of total pre-OL + SEM of four independent experiments. * indicate a significant difference (P <0.05) between treated means compared to time-matched control and # indicate a significant difference (P <0.05) compared to TNF-α or LPS treated means.

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Journal of Neuroinflammation

ISSN: 1742-2094