Figure 5
From: Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury
Microglia show expression of NOX2, NOX3, and NOX4 in vitro . After stimulation with LPS, the distribution of NOX2 changes to surround the nucleus. In contrast, NOX3 staining disappears and the intensity of NOX4 staining increases with LPS stimulation. Microglia stained with NOX2 and NOX4 were stimulated for 24 hours and microglia stained with NOX3 were stimulated for 2 hours. For NOX2, bar = 20 μm. For NOX3 and NOX4, bar = 50 μm.