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Table 3 Allele and genotype distribution of the five selected SNPs in cerebral palsy patients and controls

From: The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy

 

Group

Allele frequency

P value

Genotype frequency

P value

Hardy-Weinberg equilibrium

rs1800796

 

C

G

 

C/C

C/G

G/G

  

Case

977 (0.690)

439 (0.310)

0.256

347 (0.490)

283 (0.400)

78 (0.110)

0.300

0.081

Control

992 (0.670)

488 (0.330)

334 (0.451)

324 (0.438)

82 (0.111)

0.797

rs2069837

 

A

G

 

A/A

A/G

G/G

  

Case

1138 (0.807)

272 (0.193)

0.062

469 (0.665)

200 (0.284)

36 (0.051)

0.144

0.018

Control

1134 (0.779)

322 (0.221)

448 (0.615)

238 (0.327)

42 (0.058)

0.169

rs2066992

 

G

T

 

G/G

G/T

T/T

  

Case

441 (0.311)

977 (0.689)

0.389

77 (0.109)

287 (0.405)

345 (0.487)

0.316

0.140

Control

483 (0.326)

999 (0.674)

77 (0.104)

329 (0.444)

335 (0.452)

0.775

rs2069840

 

C

G

 

C/C

C/G

G/G

  

Case

1300 (0.913)

124 (0.087)

0.503

591 (0.830)

118 (0.166)

3 (0.004)

0.787

0.258

Control

1346 (0.906)

140 (0.094)

607 (0.817)

132 (0.178)

4 (0.005)

0.265

rs10242595

 

A

G

 

A/A

A/G

G/G

  

Case

1255 (0.891)

153 (0.109)

0.435

560 (0.795)

135 (0.192)

9 (0.013)

0.498

0.789

Control

1279 (0.882)

171 (0.118)

569 (0.785)

141 (0.194)

15 (0.021)

0.079