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Table 1 Affinities (Kd) of 2H6 and De-2H6 for antigen and effector proteins

From: Intracranial administration of deglycosylated C-terminal-specific anti-Aβ antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

Antibody

Aß1–40 (nM)

mFcγRI (μM)

mFcγRIIb (μM)

mFcγRIII (μM)

hC1q (μM)

2H6

8

1.6

20

39

5

De-2H6

9

6.5

30

67

30

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Journal of Neuroinflammation

ISSN: 1742-2094