Fig. 11
From: Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo
Hippocampal responses to nPM exposure in vivo. Mouse in vivo: Chronic nPM exposure induced components of the TLR4 pathway in hippocampus. mRNA responses by q-PCR are given, shown in relation to pathway (Fig. 7). a TLR4 mRNA was induced by nPM (p < 0.05). b MyD88 mRNA was increased by nPM (p < 0.05). c TRAF6 mRNA was decreased by nPM (p < 0.0001). d NF-κB was decreased by nPM (p < 0.05). e TNFα mRNA was increased by nPM (p < 0.01). f TNFR2 mRNA was increased by nPM (p < 0.05). n = 7