Fig. 1
From: Acute neuroinflammation induces AIS structural plasticity in a NOX2-dependent manner
LPS-induced inflammation disrupts AISs. a–f AISs in layer V of the cerebral cortex identified by ankG immunolabeling in saline- (a) and LPS-treated (b–f) mice. AIS detection is lost with time in LPS-treated mice through 1 week post-injection. However, by 2 weeks post-injection, AIS number returns to control levels, demonstrating reversibility of AIS disruption. Scale bar = 20 μM. g The mean ± SEM of AISs/FOV in saline- and LPS-treated mice as a percent of saline controls. An asterisk indicates significant difference (p < 0.05) from saline, and a ¥ indicates a difference between time points