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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Environmental noise stress disturbs commensal microbiota homeostasis and induces oxi-inflammmation and AD-like neuropathology through epithelial barrier disruption in the EOAD mouse model

Fig. 5

Intestinal abnormalities of host inflammatory responses following noise exposure. a–d Enzyme-linked immunosorbent assay analysis of inflammatory mediators (IL-6, NF-κB, iNOS, and NGAL) content in each group (n = 5–6). Data are presented as the mean ± standard deviation. *P < 0.05, **P < 0.01 vs. WT CON group; #P < 0.05, ##P < 0.01 vs. APP/PS1 CON group. §, exposure effect, P < 0.05; ¶, genotype effect, P < 0.05; ǂ, interaction effect, P < 0.05. CON, control groups; NOISE, noise-exposed groups; WT, wild-type mice; APP/PS1, APP/PS1 transgenic mice

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Journal of Neuroinflammation

ISSN: 1742-2094