Fig. 3

Weight changes and survival throughout the experiment. a DSS treatment (red lines with either saline control (Con) or LPS-paraquat co-administration) caused marked sickness and mice reached endpoint in 7 days following cessation of DSS treatment (25–30% reached endpoint). b DSS-treated animals lost weight 48 h after cessation of DSS treatment (pre-surgery weight) (p < 0.001) and c by the end of the experiment, the VSL#3-treated animals recovered, while LPS and paraquat treatment reduced weight gain in control and DSS administered mice (p < 0.01). **p < 0.01 compared to controls. ***p < 0.001 compared to other water treatment groups