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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: MicroRNA-210 downregulates TET2 and contributes to inflammatory response in neonatal hypoxic-ischemic brain injury

Fig. 4

TET2 knockdown augmented acetyl-p65 level after neonatal HI. Either TET2 siRNA (100 pmol; si. Tet2) or scramble (si. Ctrl) was administered into the right hemisphere of both male and female mouse brain via i.c.v. injection, neonatal HI was induced 48 h after siRNA injection, and the ipsilateral cerebral hemisphere of the brain was collected 12 h after HI. Acetyl-p65 and total p65 protein levels were detected by Western blot. Data are expressed as mean ± SEM. n = 6 pups/group. *p < 0.05 vs Sham

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Journal of Neuroinflammation

ISSN: 1742-2094