Fig. 2

PF543 reduces structural tissue damage, reduces neuron loss, and promotes the recovery of motor function after experimental acute spinal cord injury. a Basso, Beattie and Bresnahan (BBB) scores. b Inclined plane test scores. c H&E stains at 7 days. Scale bars are 200 μm (× 4) and 100 μm (× 20). Dashed line area shows cavity of spinal cord. d Graphic presentation of the percentage of preserved tissue relative to the transverse area of the spinal cord on the seventh day after surgery. e Nissl staining to assess the loss of neurons at 7 days (scale bar: 100 μm). f Counting analysis of ventral neurons at rostral 5 mm and caudal 5 mm. n = 5 per group. *P < 0.05 and **P < 0.01