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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Transcriptome profiling of long noncoding RNAs and mRNAs in spinal cord of a rat model of paclitaxel-induced peripheral neuropathy identifies potential mechanisms mediating neuroinflammation and pain

Fig. 1

The rat model of PIPN exhibits persistent mechanical and thermal hypersensitivities. a Experimental protocol for the establishment of the rat model of paclitaxel-induced peripheral neuropathy (PIPN). b 50% paw withdraw threshold (PWT) of right hind paw of control and Pac group rats. c Normalized AUC analysis of panel (b). d 50% paw withdraw latency (PWL) of right hind paw of control and Pac group rats. e Normalized AUC analysis of panel (d). AUCs were all normalized to corresponding control group. **p < 0.01 vs. control group. n = 5 rats/group. Two-way ANOVA followed by Tukey post hoc test was used for statistical analysis in panels (b and d), whereas Student’s t test was used for statistical analysis in panels (c and e)

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Journal of Neuroinflammation

ISSN: 1742-2094