Fig. 4From: Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of lifeGestational sepsis downregulates synaptophysin and PSD95 expression, and induces immune activation in neonates’ brains at P8. a–d Western Blot was performed to detect synaptophysin and β-tubulin in the hippocampus (a), neocortex (b), frontal cortex (c), and cerebellum (d). Each bar is the mean +/− SEM from 4 to 6 animals. e–h Western blot was performed to detect PSD95 and β-tubulin in the hippocampus (e), neocortex (f), frontal cortex (g), and cerebellum (h). Each bar is the mean +/− SEM from 3 to 4 animals. (I – L) The immune response at P8 was evaluated through TNF-α, IL-1β, and IL-6 levels analyzed by ELISA in the hippocampus (i), neocortex (j), frontal cortex (k), and cerebellum (l). Each bar is the mean +/− SEM from 3 animals from different litter each one. *p < 0.05 compared saline to sepsis. NS not significantBack to article page