Fig. 3

Quantification of the number of pro-inflammatory and immunosuppressive macrophages in WT and Cryab^−/− crushed sciatic nerves. Representative images and quantification of the number of CD16/32⁺ Iba1⁺ DAPI⁺ (a, c) and CD206⁺ Iba1⁺ DAPI⁺ (b, d) profiles in the sciatic nerves of naïve (N), and 3, 5, 7, 14, 21, and 28 days post-crushed WT (white bars) and Cryab^−/− (black bars) animals; representative of 2 experiments, n=3–4 animals/group, bar = 20 μm, data represent mean ± sem, *p< 0.05 independent t-test. e Graph displaying the ratio of CD16/32⁺ cells to CD206⁺ cells for WT and Cryab^−/− nerves