Fig. 4From: Spatial learning and memory deficits induced by prenatal glucocorticoid exposure depend on hippocampal CRHR1 and CXCL5 signaling in ratsAntalarmin treatment improves spatial learning and memory in DEX offspring. DEX offspring of 2 days old were subcutaneously administered with antalarmin (10mg/kg/day, 30mg/kg/day) for 7 days as described in the “Materials and methods” section. Morris water maze test was performed on these rats in adulthood. a, b The escape latencies of female (a) and male (b) DEX offspring in the 4-day platform acquisition training. c, the time that spent in the correct platform quadrant in the probe trial after training. d&e, the swimming speed of the rats. Data are presented as mean ± SEM (n=12 in each group). #P<0.05, ##P<0.01 vs DEX. CTL: control; anta: antalarminBack to article page