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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Traumatic brain injury results in unique microglial and astrocyte transcriptomes enriched for type I interferon response

Fig. 9

TBI-induced microglial and astrocyte transcriptomes only partially overlap with gene signatures from other neurodegenerative and neuroinflammatory conditions. A Heatmap comparing expression (Z score log-normalized counts) of disease-associated microglia genes in microglia following sham or FPI. B Heatmap comparing expression (Z score log-normalized counts) of reactive astrocyte marker genes in astrocytes following sham or FPI. Asterisks (*) indicate significantly different expression in FPI vs sham samples (adj. p < 0.1 and log2FC > 0.6) from DESeq2 analysis. n = 5 animals per condition

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