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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressure

Fig. 2

P2X7 receptor stimulation of retina from Cx3CR1+/GFP mice shows activation. a, b Retinal whole mounts isolated from Cx3CR1+/GFP mice revealed increased fluorescence at the optic nerve head compared to control media (a) after exposure to 200 μM BzATP for 2 h in a petri dish (b). This elevation in fluorescence was also seen in the middle nasal areas when comparing control media (c) to BzATP exposure (d). e, f Z-projection of middle nasal retinae exposed to control media or BzATP. Bar = 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094