Fig. 15
From: Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
Impact of Nrf2 inhibitor on EDA-induced Sirt1/Nrf2/HO-1/Gpx4 signaling pathway in the Hip of CSDS mice. A Representative WB bands. B–E Protein levels of Sirt1 (B), Nrf2 (C), HO-1 (D), and Gpx4 (E) in the Hip. Data are presented as mean ± SEM (n = 3 per group). *p < 0.05, **p < 0.01, ***p < 0.001 versus the CON group. #p < 0.05, ###p < 0.001 versus the CSDS group. &&p < 0.01, &&&p < 0.001 versus the CSDS + EDA group