Fig. 8From: PLPP/CIN-mediated NF2 S10 dephosphorylation distinctly regulates kainate-induced seizure susceptibility and neuronal death through PAK1-NF-κB-COX-2-PTGES2 signaling pathwayScheme of the role of PLPP/CIN-mediated NF2 S10 dephosphorylation in response to KA. Following KA treatment, PLPP/CIN-mediated NF2 S10 dephosphorylation may activate PAK1-NF-κB-COX-2-PTGES2 signaling pathway in neurons, which would subsequently increase the latency of seizure on-set and CA3 neuronal damage in response to KABack to article page