Fig. 5From: Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septumA–F Cumulative line graphs and corresponding area under the curve (AUC) bar graphs, representing the effects of aging and neuroinflammation on ChAT+ cholinergic cell dendritic arborization complexity in the medial septum (MS), measured by Sholl analysis. Quantitative analysis of individual ChAT+ cell dendritic arborization complexity including: A intersections (n), B length (µm), C surface area (µm2), D volume (µm3), E average diameter (µm), and F nodes (n) of young (n = 25), adult (n = 25) and old (n = 25) mice from control and GFAP-IL6 cohorts. Data presented as mean ± SEM and analysed with two-way ANOVA followed by Tukey’s post hoc tests. Post hoc effects of ‘genotype’ are represented in asterisks (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001); post hoc effects of ‘age’ are represented by hash symbols (#p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001)Back to article page