Fig. 6

A–F Representative bright-field microscopy images revealing degenerating fibres in the medial septum (MS) during aging and neuroinflammation. While background silver-staining of nuclei was visible in all sections, silver-stained fibres were not prominently observed in the sections from A young control mice compared to much aged control mice B adult and C old. The GFAP-IL6 mice D–F presented with darkly stained fibres at all three time points, with highest intensity staining in old mice. Images taken under the 20 × objective (scale bar 40 µm)