Fig. 2
From: Noteworthy perspectives on microglia in neuropsychiatric disorders
Microglial contribution to neuropsychiatric disorders. Since embryonic period, biological and social stress hijack microglia to dysfunctional states that trigger neuroinflammation, synaptic abnormality, and diminished neurogenesis in various brain areas responsible for emotional and behavioral regulation, which consequently predispose individuals to the onset or deterioration of neuropsychiatric disorders. Further understanding of microglia will shed light on the microglia-targeted therapeutics for more efficient and personalized treatment of neuropsychiatric disorders