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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Downregulation of the glucose transporter GLUT 1 in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice

Fig. 3

The effects of surgery on the metabolomic profiles in aged mice. A Heatmap of metabolites in the postsurgical hippocampus on POD 14. B PLSDA scores plot. C VIP scores of the PLSDA model. D, E Histogram showing relative changes in D ATP; E Adenosine; F Glyceraldehyde-3P and G glucose; Student’s t test with n = 3 mice per group. Data presented as mean ± SEM, *P < 0.05. PLSDA: Partial least squares discriminant analysis. VIP scores, variable of importance scores; P, phosphate; SEVO, sevoflurane; LAP, laparotomy

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