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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

Fig. 10

The Tai Chi mechanism underlying the complex regulatory effect of the neuroendocrine system on SCI-IDS. The Tai Chi diagram shows that the main tissues and organs involved in neuroendocrine immunity are the hypothalamus, adrenal glands and spleen, which are also important components of the HPA axis (from the inside out, the most central). Multitissue transcriptome analysis showed that the pathway-gene target map was composed of DEGs and the GO pathways in which they were enriched after T3-SCI; red indicates upregulation, and green indicates downregulation (second and third layers). Possible mechanisms of NIA regulation after SCI (outermost)

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