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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency

Fig. 4

Changes in gene expression in the hypothalamus after T3-SCI. A Volcano plot of DEGs between the sham group and the T3-SCI group; green indicates upregulated DEGs, and red indicates downregulated DEGs. B Volcano plot of DEGs between the T10-SCI group and the T3-SCI group. Green indicates upregulated DEGs, and red indicates downregulated DEGs. C Venn diagram analysis of common upregulated DEGs between the sham group and the T3-SCI group and between the T10-SCI group and the T3-SCI group. The red numbers represent upregulated DEGs specific to rats in the T3-SCI group in both comparisons. D Venn diagram analysis of common downregulated DEGs between the sham group and the T3-SCI group and between the T10-SCI group and the T3-SCI group. The red numbers represent downregulated DEGs specific to rats in the T3-SCI group in both comparisons. E GO enrichment analysis of the upregulated DEGs in the T3-SCI group identified by Venn diagram analysis (C). F The top 20 enriched GO terms for the downregulated DEGs in the T3-SCI group identified by Venn diagram analysis (D)

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Journal of Neuroinflammation

ISSN: 1742-2094