Fig. 10
Reduction in Microglial Ripk2 expression reduces neuroinflammatory gene expression after ischemic stroke. A Schematic of our isolation of RNA from the ipsilateral cortex (CXI) of WT and μKO mice and nanoString protocol. B Volcano plot displaying gene expression levels in the CXI 48 h after stroke. P values were – Log10 transformed; statistically significant genes fall above the horizontal line. Highly differentially expressed genes (with fold change >  ± 1.4) fall to either side of the vertical lines on either side of the zero on the x-axis. Relevant genes are labeled. C Heat map of relevant differentially expressed genes with pathway analysis. Columns represent an individual sample from each genotype