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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Receptor-interacting protein kinase 2 (RIPK2) profoundly contributes to post-stroke neuroinflammation and behavioral deficits with microglia as unique perpetrators

Fig. 3

Reduced immune cell infiltration and activation in Ripk2 deficient mice compared to controls. A Iba-1 staining of coronal brain sections 6 h after stroke injury with representative images of the ipsilateral (ipsi) and contralateral (contra) areas of interest. B, C Densitometric analysis and quantification of the area of Iba-1 staining in the cortex (B) and subcortex (C). D RT-qPCR for Nos2, Icam1, and Ly6g in the ipsi and contra cortices 24 h after stroke. A–C n = 3/group. D n = 9–11/group. Differences determined by two-way ANOVA, multiple comparisons, Turkey’s multiple comparison test. *P < 0.05, ***P < 0.001

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Journal of Neuroinflammation

ISSN: 1742-2094