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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Inhibition of adult hippocampal neurogenesis induced by postoperative CD8 + T-cell infiltration is associated with cognitive decline later following surgery in adult mice

Fig. 1

Postoperative cognitive decline persists up to the fourth week following surgery in adult mice. A Experimental protocol diagram; B swimming speeds of mice during training days in the MWM; C the number of total arm entries in the Y maze; D, H Escape latencies during training days in the MWM; E, I Times of target crossings on the testing day in the MWM; F, J Percentages of time spent in the target zone on the testing day in the MWM; G, K Spontaneous alternation rate in the Y maze. D, day post operation; MWM, Morris water maze; C, control; S2/S3/S4, animals that underwent behavioral testing at weeks 2/3/4 after surgery. N = 16–20/group. S4 vs. C, *p < 0.05, **p < 0.01; S4 vs. S2, #p < 0.05, ##p < 0.01

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Journal of Neuroinflammation

ISSN: 1742-2094