Fig. 4

A The number of studies (n) that showed neuroprotection (white) or no protection (black) after administering the treatment at ≤ 1 h, 4 h, 14 h, 2 d or 3 d before the insult. B The number of studies (n) that showed neuroprotection (white) or no protection (black) after administering the treatment at < 1 h, 1–6 h, 18 h, 1 d, 2 d, or 3 d after the insult. C The number of studies (n) that showed neuroprotection (white) or no protection (black) stratified by survival time after the insult