Fig. 1

Associations between acute-phase plasma protein levels and 3-month functional outcome in 534 ischemic stroke cases. A Odds ratios and 95% confidence intervals for unfavorable outcome per doubling of protein levels as compared to favorable outcome. Associations with false discovery rate (FDR) < 0.05 are marked in bold and black, and suggestive associations (FDR ≥ 0.05 and P < 0.05) in grey. B Hierarchical protein clusters based on Euclidean distance. Pearson’s correlation coefficients (r) between proteins are displayed, where correlations with P < 0.05 are marked in colour. Positive correlations, red; and inverse correlations, blue. C Volcano plots showing fold-change in proteins between the favorable and unfavorable outcome groups. Blue circles, proteins with > 20% higher levels in unfavorable vs favorable outcome; red circles, proteins with < 20% lower levels in unfavorable outcome; grey circles, no significant fold-change. Protein names are provided in Additional file 1: Table S1