Table 1 Baseline characteristics of ischemic stroke cases in SAHLSIS for the whole study cohort, and for the favorable and unfavorable 3-month functional outcome groups
Total | Favorable | Unfavorable | |
|---|---|---|---|
n | 534 | 415 | 119 |
Age, median [IQR], years | 58 [52–64] | 58 [52–64] | 59 [53–65] |
Male sex, n (%) | 340 (64) | 258 (62) | 82 (69) |
Timing of blood draw, median [IQR], days after index stroke | 4 [3–6] | 4 [3–6] | 4 [2–6] |
Hypertension, n (%) | 320 (60) | 247 (59) | 73 (63) |
Diabetes mellitus, n (%) | 100 (19) | 73 (18) | 27 (23)* |
Hyperlipidemia, n (%) | 379 (71) | 295 (74) | 84 (80) |
Smoking, n (%) | 208 (39) | 164 (40) | 44 (37) |
Body mass index, median [IQR], kg/m2 | 26 [24–29] | 26 [24–29] | 26 [23–29] |
Stroke severity, maximum NIHSS score, median [IQR] | 3 [2–7] | 2 [1–4] | 12 [7–16]† |
Etiological subtype of ischemic stroke (TOAST) | |||
Large artery atherosclerosis, n (%) | 68 (12) | 48 (11) | 20 (15)* |
Small artery occlusion, n (%) | 115 (20) | 104 (24) | 11 (8) |
Cardioembolic, n (%) | 97 (17) | 67 (15) | 30 (23) |
Cryptogenic, n (%) | 154 (27) | 122 (28) | 32 (24) |
Cervical arterial dissection, n (%) | 30 (5) | 17 (4) | 13 (10) |
Other determined, n (%) | 17 (3) | 12 (3) | 5 (4) |
Undetermined, n (%) | 88 (15) | 68 (15) | 20 (15) |
Stratified analyses (n) | |||
Sex, males vs females | 340 vs 194 | 258 vs 157 | 82 vs 37 |
Sensitivity analyses (n) | |||
Excluding n = 16 cases with signs of infection | 518 | 408 | 110 |
Excluding n = 23 cases with recurrent stroke/other major vascular event | 511 | 403 | 108 |
Excluding n = 67 with lipid-lowering treatment | 467 | 365 | 102 |