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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease

Fig. 5

Nisin abrogates the deposition of Aβ42, Tau, and phosphorylated Tau in the brain following oral polymicrobial infection. To evaluate the effect of nisin on modulating brain pathological changes, ELISA analysis was conducted to determine the levels of Aβ42 (A), total Tau (B) and phosphorylated Tau (C) in brain homogenates. Data are shown as means ± standard deviation from 6 mice per group. *, the difference between the two groups was significant (P < 0.05). **, the difference between the two groups was significant (P < 0.01). ***, the difference between the two groups was significant (P < 0.001), ns, the difference between the two groups was non-significant

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Journal of Neuroinflammation

ISSN: 1742-2094