Fig. 4

CD13 KO mice had increased tissue loss, inflammation, and white matter injury at day 30 post-MCAO. A Ventricle area. B percentage tissue loss at day 30 post-MCAO. C Neuron counts day 30 post-MCAO. D Iba-1 and E GFAP counts in the peri-infarct area. F MBP intensity in CC and G striatum. H increased Iba-1 and I GFAP counts in CC at day 30 post-MCAO. Magnification 20X. Scale bar 50 µm. Data presented as mean ± SEM. Three-group data were analyzed by ordinary one-way ANOVA with Tukey’s multiple comparisons test. n = 6/gp. (*p < 0.05, **p < 0.01, ***p < 0.001)