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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: BAFF blockade in experimental autoimmune encephalomyelitis reduces inflammation in the meninges and synaptic and neuronal loss in adjacent brain regions

Fig. 4

Leptomeningeal inflammation quantification using contrast enhancement in ultra-high field MRI. A Comparison of MRI scans across three time points (6, 8, and 10 weeks after immunization) in anti-BAFF treatment and IgG control groups. The yellow arrows identify areas of leptomeningeal contrast enhancement. B The total volume of leptomeningeal enhancement (LME) was averaged for each treatment group at each MRI time point. A mixed-effects analysis of the anti-BAFF treatment group (n = 19) and IgG control group (n = 18) did not show an interaction effect between time and treatment on mean volume of leptomeningeal contrast enhancements (P = 0.12)

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Journal of Neuroinflammation

ISSN: 1742-2094