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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells

Fig. 2

PLX3397 does not affect immune cell numbers in lymphoid and non-lymphoid organs (bone marrow and spleen). Bar graphs show the number of immune cells from the bone marrow: a CD3+, b CD4+, c CD8a+, d NK1.1+, e CD19+, f CD11b+Ly6G+, g MHCII+, h CD11b+Ly6Clow (patrolling monocytes), i CD11b+Ly6Chigh (inflammatory monocytes); and the spleen: j CD3+, k CD4+, l CD8a+, m NK1.1+, n CD19+, o CD11b+Ly6G+, p MHCII+, q CD11b+Ly6Clow (patrolling monocytes) , r CD11b+Ly6Chigh (inflammatory monocytes). Data were analyzed with unpaired Student’s T-test, n = 3–6, and data represented by mean ± SEM, *p < 0.05

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