Fig. 5

Innate immune cell numbers are negatively impacted by PLX3397 in lymphoid and non-lymphoid organs after LPS infection. Bar graphs show the number of immune cells from the spleen: a CD3⁺, b CD4⁺, c CD8a⁺, d NK1.1⁺, e CD19⁺, f CD11b⁺Ly6G⁺ (neutrophils), g CD11b⁺Ly6C^high (inflammatory monocytes), h CD11b⁺Ly6C_low (patrolling monocytes), i MHCII⁺; and the lung: j CD3⁺, k CD4⁺, l CD8a⁺, m NK1.1⁺, n CD19⁺, o CD11b⁺Ly6G⁺ (neutrophils), p CD11b⁺Ly6C^high (inflammatory monocytes), q CD11b⁺Ly6C_low (patrolling monocytes), r MHCII⁺. Data were analyzed with unpaired Student’s T-test, n = 3–4, and data represented by mean ± SEM, *p < 0.05, **p < 0.01