Skip to main content
Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells

Fig. 7

PLX3397 does not affect LPS-induced sickness behavior. a, b Effects of LPS on a body weight and b body temperature measured 6 h after intraperitoneal LPS injection in PLX3397-fed mice compared to control chow-fed mice, c representative images of mouse exploration without and following LPS. d–f Quantification of locomotor activity measured by d distance traveled, e velocity and f time in center in an open-field test carried out 6 h post-LPS. Data represented by mean ± SEM, n = 5, ***p < 0.001, ****p < 0.0001

Back to article page