Fig. 2

Macrophage subtypes are altered in Nr4a1^−/− and Nr4a1^se2/se2 eyes. A Representative macrophage plots from control and laser-treated WT, Nr4a1^−/−, and Nr4a1^se2/se2 eyes. B–E Number of MHCII⁺CD11c^neg (B), MHCII⁺CD11c⁺ (C), MHCII^negCD11c^neg (D), and MHCII^negCD11c⁺ (E) macrophages from each group. N = 7–23 mice per group. Two-way ANOVA followed by Sidak’s multiple comparisons test *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Mac macrophage, WT wildtype