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Table 1 Characteristics of the study populations

From: Alterations in pathogen-specific cellular and humoral immunity associated with acute peripheral facial palsy of infectious origin

 

PFP-patients

Controls

p-value

n

55

23

 

Years of age [mean ± SD]

46.89 ± 19.3

43.1 ± 17.4

0.413

Females [n (%)]

21 (38.2%)

14 (60.9%)

0.089

Leukocytes/µl blood

[median (IQR)]

7200 (3260)

6980 (2370)

0.042

% lymphocytes in blood

[median (IQR)]

26.0 (11.1)

33.1 (5.4)

0.002

Neutrophil/lymphocyte ratio

[median (IQR)]

2.42 (1.47)

1.73 (0.48)

0.004

Days between 1st and 2nd

blood sampling, [mean ± SD]

13.8 ± 2.1

(n = 36)

14.0 ± 1.0

(n = 15)

0.996

Clinical characteristics PFP

   

Days since onset of symptoms

[mean ± SD]

2.6 ± 2.1

n.a

 

House–Brackmann grading (1–6)

[median (IQR)]#

3.5 (1.5)

n.a

 

PFP side

   

Left

Right

Bilateral

32 (58.2%)

21 (38.2%)

2 (3.6%)

n.a

n.a

n.a

 

Lumbar puncture§

(n = 47)

n.a

 

Normal cell counts (0–4 cells/µl)

Borderline (5 cells/µl)

Pleocytosis (> 5 cells/µl)*

35 (74.5%)

4 (8.5%)

8 (17.0%)

n.a

n.a

n.a

 

PFP-treatment [n]$

52

n.a

 

Steroids

32

  

Anti-bacterialb

1

  

Steroids/anti-virala

2

  

Anti-virala/anti-bacterialb

7

  

Steroids/anti-virala/anti-bacterialb

8

  

Immunoglobulins

2

  
  1. #House–Brackmann grading was not available in 3 patients; 1–6 corresponds to I–VI
  2. $3 patients with symptomatic treatment only
  3. §lumbar puncture was not possible in 8 cases due to either oral anticoagulation (n = 6) or lack of consent (n = 2)
  4. *median 14 (IQR 70.8) cells/µl
  5. ai.e., (val)acyclovir
  6. bi.e., ceftriaxone, doxycycline or ampicillin