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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage

Fig. 10

Effects of recombinant Slit2 on long-term neurobehaviors after GMH. Recombinant Slit2 improved the performances on Water Maze test (A, B) and Rotarod test (C) in GMH rats, which were reversed either by co-administration of rRobo1 or srGAP1 siRNA. N = 6/group. Mean ± SEM. ANOVA, Tukey. *P < 0.05 vs. Sham, #P < 0.05 vs. GMH + Vehicle, &P < 0.05 vs. GMH + rSlit2, @P < 0.05 vs. GMH + rSlit2 + scrambled siRNA

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Journal of Neuroinflammation

ISSN: 1742-2094