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Table 4 The associations between SAI as the dependent variable and other risk factors for poor outcome

From: Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study

Model/p-value for model

Age

Male sex

NIHSS D1

Ischemic lesion volume D1

Added variable: leukocytes/leukocyte subset

OR (95% CI); p-value

Model 1

p < 0.001

0.99

(0.97–1.03);

0.99

1.12

(0.45–2.77)

0.79

1.36

(1.28–1.46)

 < 0.001

1.21

(1.18–1.21)

0.03

Model 2

p < 0.001

1.01

(0.96–1.04);

0.76

1.04

(0.39–2.77)

0.92

1.32

(1.22–1.43)

0.008

1.21

(1.17–1.23)

0.04

WBC D3

1.64

(1.34–2.01)

0.001

Model 3

p < 0.001

0.99

(0.95–1.03);

0.74

1.16

(0.46–2.92)

0.75

1.33

(1.24–1.43)

0.003

1.21

(1.17–1.24)

0.04

Lymphocytes % D3

0.94

(0.89–1.00)

0.05

Model 4

p < 0.001

0.68

(0.1–4.48);

0.69

1.09

(0.58–2.05)

0.79

1.37

(1.28–1.47)

 < 0.001

1.21

(1.18–1.24)

0.04

Treg%CD3 D3

0.67

(0.32–1.39)

0.28

Model 5

p < 0.001

0.99

(0.96–1.03);

0.84

1.15

(0.46–2.87)

0.76

1.34

(1.28–1.46)

0.001

1.21

(1.18–1.24)

0.04

H+ % Treg D3

1.29

(1.08–1.27)

0.02

  1. Multivariate logistic regression models describe the associations between stroke-associated infection (SAI) as the dependent variable and other risk factors for poor outcome including immune response cells
  2. Values in bold are statistically significant
  3. WBC—white blood cells; lymphocytes—percentage of lymphocytes in leukocyte population (automatic blood smear); Treg%CD3—percentage of Tregs in lymphocyte population (flow cytometry); H+ %Treg—percentage of Tregs with Helios expression in Treg population (flow cytometry); NIHSS—National Institutes of Health Scale Score; D1, D3—days after stroke