Fig. 8From: OTUD1 ameliorates cerebral ischemic injury through inhibiting inflammation by disrupting K63-linked deubiquitination of RIP2Proposed model of OTUD1 regulated RIP2-mediated inflammation in ischemic stroke. OTUD1 ameliorated brain injury after ischemia through inhibiting RIP2-mediated NF-κB activation to prevent cerebral inflammation by specifically cleaving K63-linked ubiquitination of RIP2Back to article page