Fig. 2

Effects of experimental intervention on novel object recognition and MWM test (n = 10 mice/group). A Swimming path; B escape latency, a*: SR1001 group, Day 1 vs Day 5, p = 0.038; b*: P60 group, Day 1 vs Day 5, p = 0.019, b^: P60 group, Day 2 vs Day 5, p = 0.019; c*: 27-OHC + SR1001 group, Day 1 vs Day 5, p = 0.003, c^: 27-OHC + SR1001 group, Day 2 vs Day 5, p = 0.003, c&: 27-OHC + SR1001 group, Day 3 vs Day 5, p = 0.010; C mean distance to platform; D distance in the target quadrant (%); E time in the target quadrant (%); F average speed; G the number of platform-site crossovers; H novel object recognition index (NORI) = Fn/Tn × 100% (Fn: exploring frequency of novel object; Tn: exploring time of novel object). All data are presented as mean ± SD. *p < 0.05. **p < 0.01